Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.41 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.41 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24463344 | 1.00 | FGFR1 (0.41) | FGFR1FGFR2FGFR3HSD17B10CYP17A1 | |
| SCHEMBL24463288 | 0.84 | IDO1 (0.39) | FGFR1FGFR2FGFR3HSD17B10IDO1 | |
| SCHEMBL24463571 | 0.81 | FGFR1 (0.38) | FGFR1FGFR2FGFR3HSD17B10CYP17A1 | |
| SCHEMBL26790691 | 0.80 | GRM5 (0.39) | HSD17B10GAAALDH1A1TP53HPGD | |
| SCHEMBL28995813 | 0.80 | FGFR1 (0.41) | FGFR1FGFR2FGFR3HSD17B10CYP17A1 | |
| SCHEMBL24463353 | 0.76 | CCNT1 (0.59) | ALDH1A1LMNACCNT1CDK9 | |
| SCHEMBL30461561 | 0.76 | CCNT1 (0.59) | ALDH1A1LMNACCNT1CDK9 | |
| SCHEMBL30490119 | 0.75 | GRM5 (0.43) | FGFR1FGFR2FGFR3HSD17B10GAA | |
| SCHEMBL25335186 | 0.75 | GRM5 (0.43) | FGFR1FGFR2FGFR3HSD17B10GAA | |
| SCHEMBL26791306 | 0.75 | JAK1 (0.30) | DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107870-A1 | INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES | KINNATE BIOPHARMA INC. (US) | 2023-06-15 | — | — | WO | disclosed |