Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 2/20 | 0.59 |
| ▸ | CDK9 | P50750 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 9/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 9/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24463353 | 1.00 | CCNT1 (0.59) | CCNT1CDK9KDM4EALDH1A1MAPT | |
| SCHEMBL24463254 | 0.85 | CCNT1 (0.46) | CCNT1CDK9CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL24463365 | 0.84 | CCNT1 (0.65) | CCNT1CDK9KDM4EALDH1A1MAPT | |
| SCHEMBL24463442 | 0.81 | CCNT1 (0.38) | CCNT1CDK9ALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL26790682 | 0.80 | KDM4E (0.44) | CCNT1CDK9KDM4EALDH1A1MAPT | |
| SCHEMBL24463606 | 0.77 | KDM4E (0.51) | CCNT1CDK9KDM4EALDH1A1MAPT | |
| SCHEMBL30461533 | 0.76 | FGFR1 (0.41) | CCNT1CDK9ALDH1A1LMNA | |
| SCHEMBL24463344 | 0.76 | FGFR1 (0.41) | CCNT1CDK9ALDH1A1LMNA | |
| SCHEMBL26790884 | 0.75 | FGFR2 (0.34) | CCNT1CDK9 | |
| SCHEMBL24463435 | 0.75 | CDK9 (0.68) | CCNT1CDK9KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107870-A1 | INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES | KINNATE BIOPHARMA INC. (US) | 2023-06-15 | — | — | WO | disclosed |