Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 17/20 | 0.46 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.41 |
| ▸ | WDR48 | Q8TAF3 | 5/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26627854 | 1.00 | USP1 (0.46) | USP1PIP4K2CWDR48GRM5ALOX5AP | |
| SCHEMBL30707897 | 0.85 | USP1 (0.37) | USP1GRM5ALOX5APFEN1 | |
| SCHEMBL26627766 | 0.78 | USP1 (0.44) | USP1 | |
| SCHEMBL30462041 | 0.78 | USP1 (0.44) | USP1 | |
| SCHEMBL5332952 | 0.77 | GRM5 (0.48) | GRM5ALOX5APFEN1 | |
| SCHEMBL30278074 | 0.73 | PIK3CD (0.41) | — | |
| SCHEMBL29904794 | 0.72 | USP1 (0.43) | USP1PIP4K2CWDR48 | |
| SCHEMBL30698033 | 0.72 | NPC1 (0.43) | GRM5ALOX5APFEN1 | |
| SCHEMBL30277907 | 0.70 | GRM5 (0.33) | GRM5 | |
| SCHEMBL16692863 | 0.69 | GRM5 (0.40) | GRM5ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118660872-A | Pyrimidine compound, preparation method and medical application thereof | 江苏亚虹医药科技股份有限公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-116496252-A | Pyrimidine compound, preparation method and medical application thereof | 江苏亚虹医药科技股份有限公司 | 2023-07-28 | — | — | CN | disclosed |