Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.62 |
| ▸ | THPO | P40225 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.62 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.62 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.62 |
| ▸ | ACHE | P22303 | 1/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.62 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.62 |
| ▸ | DRD3 | P35462 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29038261 | 1.00 | SMN1; SMN2 (0.62) | SMN1; SMN2LMNACYP3A4ALDH1A1HIF1A | |
| SCHEMBL1071414 | 0.95 | SMN1; SMN2 (0.68) | SMN1; SMN2LMNACYP3A4ALDH1A1HIF1A | |
| SCHEMBL1067494 | 0.94 | CYP3A4 (0.51) | SMN1; SMN2LMNACYP3A4ALDH1A1HIF1A | |
| SCHEMBL1069268 | 0.84 | CYP3A4 (0.49) | SMN1; SMN2LMNACYP3A4ALDH1A1HIF1A | |
| SCHEMBL5024973 | 0.83 | HIF1A (0.89) | SMN1; SMN2LMNACYP3A4ALDH1A1HIF1A | |
| SCHEMBL1069263 | 0.83 | ALDH1A1 (0.70) | SMN1; SMN2LMNACYP3A4ALDH1A1HIF1A | |
| SCHEMBL14956630 | 0.83 | HIF1A (0.89) | SMN1; SMN2LMNACYP3A4ALDH1A1HIF1A | |
| Hydrochloric Acid SCHEMBL2682374 | 0.82 | ALDH1A1 (0.68) | SMN1; SMN2LMNACYP3A4ALDH1A1HIF1A | |
| SCHEMBL1071994 | 0.82 | ALDH1A1 (0.52) | SMN1; SMN2LMNACYP3A4ALDH1A1HIF1A | |
| SCHEMBL4104422 | 0.81 | CYP3A4 (0.67) | SMN1; SMN2LMNACYP3A4ALDH1A1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283627-A | Synthesis method of melphalan impurity G | 深圳市江川医药技术有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-116283627-A | Synthesis method of melphalan impurity G | 深圳市江川医药技术有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116283627-A | Synthesis method of melphalan impurity G | 深圳市江川医药技术有限公司 | 2023-06-23 | — | — | CN | disclosed |