Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21327282 | 1.00 | POLB (0.49) | POLBMAPTTHRBFFAR4MTNR1A | |
| SCHEMBL16930277 | 0.93 | SMPD1 (0.56) | MTNR1AMTNR1BAPPNPC1RAB9A | |
| SCHEMBL8975189 | 0.84 | MTNR1A (0.54) | POLBMAPTTHRBFFAR4MTNR1A | |
| SCHEMBL3817639 | 0.83 | FFAR4 (0.55) | POLBMAPTTHRBFFAR4MTNR1A | |
| SCHEMBL26851429 | 0.81 | MTNR1A (0.55) | POLBMAPTTHRBFFAR4MTNR1A | |
| SCHEMBL17709303 | 0.81 | SMPD1 (0.52) | FFAR4MTNR1AMTNR1BAPPNPC1 | |
| SCHEMBL6214774 | 0.81 | FOLH1 (0.51) | POLBMAPTTHRBFFAR4MTNR1A | |
| SCHEMBL10477771 | 0.81 | FOLH1 (0.55) | POLBMAPTTHRBFFAR4MTNR1A | |
| SCHEMBL8072945 | 0.81 | PTGER1 (0.52) | POLBMAPTTHRBFFAR4MTNR1A | |
| SCHEMBL6035750 | 0.80 | MAPT (0.61) | POLBMAPTTHRBFFAR4MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116751200-A | Tricyclic compounds containing substituted pyridones and methods of using the same | 爱彼特生物制药公司 | 2023-09-15 | — | — | CN | disclosed |
| CN-110114071-B | Tricyclic compounds containing substituted pyridones and methods of using the same | 爱彼特生物制药公司 | 2023-07-04 | — | — | CN | disclosed |