Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 8/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | BCR | P11274 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28182535 | 1.00 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1KMT2ASYKMAPT | |
| SCHEMBL28182534 | 1.00 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1KMT2ASYKMAPT | |
| SCHEMBL2060711 | 0.86 | SYK (0.40) | ALDH1A1SYKMAPTABL1BCR | |
| SCHEMBL2060715 | 0.86 | SYK (0.40) | ALDH1A1SYKMAPTABL1BCR | |
| SCHEMBL2061922 | 0.86 | SYK (0.40) | ALDH1A1SYKMAPTABL1BCR | |
| SCHEMBL18634006 | 0.78 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL3565874 | 0.77 | KMT2A (0.53) | ALDH1A1L3MBTL1KMT2ASYKMAPT | |
| SCHEMBL18682777 | 0.74 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL16784842 | 0.74 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL16784839 | 0.74 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1KMT2ASYKABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107216312-B | Compound with mutant IDH inhibitory activity, preparation method and application thereof | 上海海和药物研究开发股份有限公司 | 2023-08-01 | — | — | CN | disclosed |