SCHEMBL30463240

SCHEMBL30463240

CSCC[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(C)=O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(N)=O

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SIRT5 Q9NXA8 2/20 0.51
IL23R Q5VWK5 6/20 0.46
RXFP1 Q9HBX9 2/20 0.45
TFPI P10646 1/20 0.43
SIRT6 Q8N6T7 1/20 0.43
SIRT1 Q96EB6 1/20 0.43
EIF4E P06730 1/20 0.41
EIF4EBP1 Q13541 1/20 0.41
TLR2 O60603 1/20 0.40
ESR1 P03372 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30463245 1.00 SIRT5 (0.51) SIRT5IL23RRXFP1TFPISIRT6
SCHEMBL31157691 1.00 SIRT5 (0.51) SIRT5IL23RRXFP1TFPISIRT6
SCHEMBL31157731 1.00 SIRT5 (0.51) SIRT5IL23RRXFP1TFPISIRT6
SCHEMBL31157741 0.96 SIRT5 (0.46) SIRT5IL23RRXFP1TFPISIRT6
SCHEMBL12066140 0.95 SIRT5 (0.53) SIRT5IL23RRXFP1TFPI
SCHEMBL31157760 0.95 SIRT5 (0.53) SIRT5IL23RRXFP1TFPI
SCHEMBL30998021 0.95 SIRT5 (0.53) SIRT5IL23RRXFP1TFPI
SCHEMBL31157647 0.95 SIRT5 (0.53) SIRT5IL23RRXFP1TFPI
SCHEMBL30463244 0.95 SIRT5 (0.53) SIRT5IL23RRXFP1TFPI
SCHEMBL30463260 0.95 SIRT5 (0.53) SIRT5IL23RRXFP1TFPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230190616-A1 COMPOUNDS USEFUL FOR THE TREATMENT AND/OR CARE OF THE SKIN, HAIR, NAILS AND/OR MUCOUS MEMBRANES LUBRIZOL ADVANCED MATERIALS, INC. (US) 2023-06-22 US claimed
US-20230190616-A1 COMPOUNDS USEFUL FOR THE TREATMENT AND/OR CARE OF THE SKIN, HAIR, NAILS AND/OR MUCOUS MEMBRANES LUBRIZOL ADVANCED MATERIALS, INC. (US) 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230190616-A1 COMPOUNDS USEFUL FOR THE TREATMENT AND/OR CARE OF THE SKIN, HAIR, NAILS AND/OR MUCOUS MEMBRANES GLA, ALG3, ANXA6 SIRT5 3611/4885IL23R 4335/4885RXFP1 224/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.