Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.42 |
| ▸ | NPY1R | P25929 | 2/20 | 0.42 |
| ▸ | NPY4R | P50391 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 3/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 3/20 | 0.41 |
| ▸ | CTSS | P25774 | 3/20 | 0.41 |
| ▸ | CTSK | P43235 | 3/20 | 0.41 |
| ▸ | CTSH | P09668 | 1/20 | 0.41 |
| ▸ | IL23R | Q5VWK5 | 3/20 | 0.40 |
| ▸ | TFPI | P10646 | 1/20 | 0.40 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30463254 | 1.00 | RXFP1 (0.43) | RXFP1NPY5RSIRT5NPY1RNPY4R | |
| SCHEMBL31036875 | 0.96 | SIRT5 (0.46) | RXFP1NPY5RSIRT5NPY1RNPY4R | |
| SCHEMBL12066142 | 0.96 | SIRT5 (0.46) | RXFP1NPY5RSIRT5NPY1RNPY4R | |
| SCHEMBL31157630 | 0.94 | SIRT5 (0.48) | RXFP1NPY5RSIRT5NPY1RNPY4R | |
| SCHEMBL31157658 | 0.94 | SIRT5 (0.48) | RXFP1NPY5RSIRT5NPY1RNPY4R | |
| SCHEMBL31157655 | 0.94 | SIRT5 (0.43) | RXFP1NPY5RSIRT5NPY1RNPY4R | |
| SCHEMBL31157643 | 0.93 | SIRT5 (0.48) | RXFP1NPY5RSIRT5NPY1RNPY4R | |
| SCHEMBL31157701 | 0.93 | BACE1 (0.45) | RXFP1NPY5RSIRT5NPY1RNPY4R | |
| SCHEMBL31157696 | 0.92 | IL23R (0.45) | RXFP1NPY5RSIRT5NPY1RNPY4R | |
| SCHEMBL3739792 | 0.92 | IL23R (0.45) | RXFP1NPY5RSIRT5NPY1RNPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230190616-A1 | COMPOUNDS USEFUL FOR THE TREATMENT AND/OR CARE OF THE SKIN, HAIR, NAILS AND/OR MUCOUS MEMBRANES | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230190616-A1 | COMPOUNDS USEFUL FOR THE TREATMENT AND/OR CARE OF THE SKIN, HAIR, NAILS AND/OR MUCOUS MEMBRANES | GLA, ALG3, ANXA6 | RXFP1 224/4885NPY5R 247/4885SIRT5 3611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.