Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.74 |
| ▸ | DNMT1 | P26358 | 3/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.74 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.74 |
| ▸ | PKM | P14618 | 1/20 | 0.74 |
| ▸ | STAT3 | P40763 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.52 |
| ▸ | SDCBP | O00560 | 1/20 | 0.52 |
| ▸ | SDC2 | P34741 | 1/20 | 0.52 |
| ▸ | MIF | P14174 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7664564 | 1.00 | KMT2A (0.74) | KMT2ADNMT1CYP2C19DNMT3BPKM | |
| SCHEMBL14077019 | 0.88 | DNMT1 (0.61) | KMT2ADNMT1CYP2C19DNMT3BPKM | |
| SCHEMBL14066847 | 0.87 | DNMT1 (0.60) | KMT2ADNMT1CYP2C19DNMT3BPKM | |
| SCHEMBL14066857 | 0.87 | DNMT1 (0.60) | KMT2ADNMT1CYP2C19DNMT3BPKM | |
| SCHEMBL3087159 | 0.86 | DNMT1 (0.56) | KMT2ADNMT1CYP2C19DNMT3BPKM | |
| SCHEMBL883644 | 0.86 | KMT2A (0.74) | KMT2ADNMT1CYP2C19DNMT3BPKM | |
| SCHEMBL30167914 | 0.85 | KMT2A (1.00) | KMT2ADNMT1CYP2C19DNMT3BPKM | |
| SCHEMBL562060 | 0.85 | KMT2A (1.00) | KMT2ADNMT1CYP2C19DNMT3BPKM | |
| SCHEMBL11949518 | 0.85 | KMT2A (1.00) | KMT2ADNMT1CYP2C19DNMT3BPKM | |
| SCHEMBL164192 | 0.85 | KMT2A (1.00) | KMT2ADNMT1CYP2C19DNMT3BPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112390791-B | DNA methyltransferase 1 fluorescent probe and application thereof | 复旦大学 | 2023-08-01 | — | — | CN | disclosed |