Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.50 |
| ▸ | REN | P00797 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PEPD | P12955 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.50 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29379676 | 0.95 | ACE (0.54) | ACERENKDM4EF2LMNA | |
| SCHEMBL29430534 | 0.89 | ACE (0.48) | ACERENKDM4EF2LMNA | |
| SCHEMBL23091321 | 0.88 | ACE (0.47) | ACERENKDM4EF2LMNA | |
| SCHEMBL23091320 | 0.88 | ACE (0.47) | ACERENKDM4EF2LMNA | |
| SCHEMBL23854819 | 0.88 | ACE (0.47) | ACERENKDM4EF2LMNA | |
| SCHEMBL31547785 | 0.87 | ACE (0.53) | ACERENKDM4EF2LMNA | |
| SCHEMBL9400887 | 0.85 | ACE (0.46) | ACERENKDM4EF2LMNA | |
| SCHEMBL9400901 | 0.85 | ACE (0.46) | ACERENKDM4EF2LMNA | |
| SCHEMBL30905695 | 0.84 | ACE (0.48) | ACERENKDM4EF2LMNA | |
| SCHEMBL29430558 | 0.84 | ACE (0.52) | ACERENKDM4EF2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116635050-A | Novel triple agonists active on all of glucagon, GLP-1 and GIP receptors and uses thereof | 韩美药品株式会社 | 2023-08-22 | — | — | CN | disclosed |
| CN-116209475-A | Therapeutic uses comprising a triple agonist long-acting conjugate or a combination of triple agonists | 韩美药品株式会社 | 2023-06-02 | — | — | CN | disclosed |