SCHEMBL30463515

SCHEMBL30463515

Brc1ccc2c(c1)c1ccccc1n2-c1ccc(-c2cccc3ccccc23)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
CA12 O43570 3/20 0.38
CA1 P00915 3/20 0.38
CA2 P00918 3/20 0.38
CA9 Q16790 3/20 0.38
TSPO P30536 1/20 0.36
TUBB4A P04350 1/20 0.36
TUBB P07437 1/20 0.36
TUBA3C P0DPH7 1/20 0.36
TUBA1B P68363 1/20 0.36
TUBA4A P68366 1/20 0.36
TUBB4B P68371 1/20 0.36
TUBB3 Q13509 1/20 0.36
TUBB2A Q13885 1/20 0.36
TUBB8 Q3ZCM7 1/20 0.36
TUBA3E Q6PEY2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3663582 1.00 KDM4E (0.41) KDM4EATML3MBTL1HDAC8HDAC6
SCHEMBL17402872 0.97 HDAC8 (0.41) KDM4EATML3MBTL1HDAC8HDAC6
SCHEMBL19152003 0.92 KDM4E (0.41) KDM4EATML3MBTL1HDAC8HDAC6
SCHEMBL16731338 0.89 KDM4E (0.38) KDM4EATML3MBTL1HDAC8HDAC6
SCHEMBL23370527 0.89 KDM4E (0.46) KDM4EATML3MBTL1HDAC8HDAC6
SCHEMBL10130267 0.87 CA12 (0.46) KDM4EATML3MBTL1HDAC8HDAC6
SCHEMBL25672230 0.87 L3MBTL1 (0.49) KDM4EATML3MBTL1TSPOHDAC4
SCHEMBL16731113 0.87 KDM4E (0.37) KDM4EATML3MBTL1HDAC8HDAC6
SCHEMBL3660681 0.87 KDM4E (0.53) KDM4EATML3MBTL1HDAC8HDAC6
SCHEMBL30463512 0.87 KDM4E (0.53) KDM4EATML3MBTL1HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111187199-B Carbazole derivative, and light-emitting element, light-emitting device, and electronic device using carbazole derivative 株式会社半导体能源研究所 2023-07-21 CN disclosed
CN-116375629-A Carbazole derivative, and light-emitting element, light-emitting device, and electronic device using carbazole derivative 株式会社半导体能源研究所 2023-07-04 CN disclosed
CN-116375628-A Carbazole derivative, and light-emitting element, light-emitting device, and electronic device using carbazole derivative 株式会社半导体能源研究所 2023-07-04 CN disclosed