Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 16/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28577515 | 1.00 | XDH (0.68) | XDHGAATSHRKMT2ASMN1; SMN2 | |
| SCHEMBL28563940 | 0.88 | XDH (0.65) | XDH | |
| SCHEMBL30464264 | 0.88 | XDH (0.65) | XDH | |
| SCHEMBL28568422 | 0.87 | XDH (0.66) | XDH | |
| SCHEMBL30464268 | 0.87 | XDH (0.66) | XDH | |
| SCHEMBL28566556 | 0.86 | XDH (0.69) | XDHKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL30464269 | 0.86 | XDH (0.69) | XDHKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL30464260 | 0.85 | XDH (0.68) | XDHGAAKMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL28568535 | 0.84 | XDH (0.65) | XDH | |
| SCHEMBL28429322 | 0.84 | XDH (0.72) | XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112920170-B | N- (indol-5-yl) aromatic heterocyclic amide compound and preparation method and application thereof | 中国医科大学 | 2023-06-20 | — | — | CN | disclosed |