Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 9/20 | 0.50 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.50 |
| ▸ | KDM3A | Q9Y4C1 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | KDM6B | O15054 | 3/20 | 0.50 |
| ▸ | KDM5C | P41229 | 3/20 | 0.50 |
| ▸ | KDM5A | P29375 | 5/20 | 0.47 |
| ▸ | KDM5B | Q9UGL1 | 5/20 | 0.47 |
| ▸ | KDM4A | O75164 | 2/20 | 0.47 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TET3 | O43151 | 1/20 | 0.47 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ASPH | Q12797 | 1/20 | 0.47 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.47 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.47 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.47 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.47 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2585341 | 1.00 | KDM4C (0.50) | KDM4CKDM2AKDM3AKDM4EKDM6B | |
| SCHEMBL13490849 | 0.92 | KDM4C (0.49) | KDM4CKDM2AKDM3AKDM4EKDM6B | |
| SCHEMBL2590131 | 0.86 | KDM4E (0.53) | KDM4CKDM2AKDM3AKDM4EKDM6B | |
| SCHEMBL17276016 | 0.86 | IKBKB (0.47) | KDM5CKDM5BACACBLOXL2 | |
| SCHEMBL25049489 | 0.85 | KDM4C (0.57) | KDM4CKDM2AKDM3AKDM4EKDM6B | |
| SCHEMBL12800159 | 0.84 | KDM4C (0.45) | KDM4CKDM2AKDM3AKDM4EKDM6B | |
| SCHEMBL31729821 | 0.84 | TP53 (0.55) | KDM4CKDM5AKDM5B | |
| SCHEMBL17412498 | 0.84 | PLA2G2A (0.55) | KDM4CKDM5AKDM5BALDH1A1 | |
| SCHEMBL2546283 | 0.83 | KDM4C (0.50) | KDM4CKDM2AKDM3AKDM4EKDM6B | |
| SCHEMBL1992514 | 0.81 | MAPT (0.57) | KDM4CKDM2AKDM3AKDM4EKDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116529246-A | N- [ (1, 3-benzoxazol-2-yl) -heterocycle ] amide derivatives for the treatment and prevention of hepatitis b virus infection | 豪夫迈·罗氏有限公司 | 2023-08-01 | — | — | CN | disclosed |