Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 3/20 | 0.65 |
| ▸ | MC5R | P33032 | 2/20 | 0.65 |
| ▸ | MC3R | P41968 | 2/20 | 0.65 |
| ▸ | MC1R | Q01726 | 2/20 | 0.65 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.59 |
| ▸ | IL23R | Q5VWK5 | 4/20 | 0.56 |
| ▸ | CALCA | P06881 | 2/20 | 0.56 |
| ▸ | CTSL | P07711 | 3/20 | 0.56 |
| ▸ | CTSS | P25774 | 3/20 | 0.56 |
| ▸ | CTSK | P43235 | 3/20 | 0.56 |
| ▸ | CTSH | P09668 | 1/20 | 0.55 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.54 |
| ▸ | NMBR | P28336 | 1/20 | 0.54 |
| ▸ | GRPR | P30550 | 1/20 | 0.54 |
| ▸ | GLP1R | P43220 | 2/20 | 0.51 |
| ▸ | GCGR | P47871 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30464996 | 0.97 | MC4R (0.67) | MC4RMC5RMC3RMC1RC5AR1 | |
| SCHEMBL30750450 | 0.96 | MC4R (0.71) | MC4RMC5RMC3RMC1RC5AR1 | |
| SCHEMBL30750506 | 0.94 | MC4R (0.73) | MC4RMC5RMC3RMC1RC5AR1 | |
| Afamelanotide SCHEMBL29419548 | 0.89 | MC4R (0.81) | MC4RMC5RMC3RMC1RC5AR1 | |
| Afamelanotide SCHEMBL29352792 | 0.89 | MC4R (0.81) | MC4RMC5RMC3RMC1RC5AR1 | |
| Afamelanotide SCHEMBL22463810 | 0.89 | MC4R (0.81) | MC4RMC5RMC3RMC1RC5AR1 | |
| Afamelanotide SCHEMBL22463811 | 0.89 | MC4R (0.81) | MC4RMC5RMC3RMC1RC5AR1 | |
| Afamelanotide SCHEMBL29533175 | 0.88 | MC4R (0.80) | MC4RMC5RMC3RMC1RC5AR1 | |
| SCHEMBL30427315 | 0.86 | C5AR1 (0.72) | MC4RMC5RMC3RMC1RC5AR1 | |
| SCHEMBL30464995 | 0.86 | IL23R (0.61) | MC4RIL23R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11622994-B2 | Therapy for vitiligo | CLINUVEL PHARMACEUTICALS LIMITED (AU) | 2023-04-11 | — | — | US | claimed |
| EP-3573645-B1 | ALPHA-MSH ANALOGUES USED IN THE TREATMENT OF XERODERMA PIGMENTOSUM | VALLAURIX MC S A R L (MC) | 2024-03-13 | — | — | EP | disclosed |
| EP-3030256-B1 | NDP-MSH FOR USE IN THE TREATMENT OF MULTIPLE SCLEROSIS | CLINUVEL PHARMACEUTICALS LTD (AU) | 2024-01-24 | — | — | EP | disclosed |
| US-11622994-B2 | Therapy for vitiligo | CLINUVEL PHARMACEUTICALS LIMITED (AU) | 2023-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11622994-B2 | Therapy for vitiligo | MC1R, MC3R, MC5R | MC4R 4/4885MC5R 3/4885MC3R 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.