Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 14/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 4/20 | 0.39 |
| ▸ | KDR | P35968 | 4/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3048303 | 0.89 | CHEK1 (0.42) | CHEK1AURKAKDRCDK1 | |
| Hydrochloric Acid SCHEMBL3050509 | 0.89 | CHEK1 (0.48) | CHEK1AURKAKDRCDK1 | |
| Hydrochloric Acid SCHEMBL3046777 | 0.86 | CHEK1 (0.52) | CHEK1AURKAKDRCDK1 | |
| Hydrochloric Acid SCHEMBL3050165 | 0.85 | CHEK1 (0.54) | CHEK1AURKAKDR | |
| Hydrochloric Acid SCHEMBL3048616 | 0.84 | CHEK1 (0.47) | CHEK1AURKAKDRCDK1 | |
| Hydrochloric Acid SCHEMBL3047166 | 0.84 | AURKA (0.49) | CHEK1AURKAKDRCDK1 | |
| SCHEMBL3049984 | 0.83 | KDR (0.43) | CHEK1AURKAKDRCDK1 | |
| Hydrochloric Acid SCHEMBL3048311 | 0.83 | CHEK1 (0.46) | CHEK1AURKAKDRCDK1 | |
| Hydrochloric Acid SCHEMBL3043804 | 0.83 | CHEK1 (0.44) | CHEK1AURKAKDRCDK1 | |
| Hydrochloric Acid SCHEMBL3046278 | 0.82 | CHEK1 (0.47) | CHEK1AURKAKDRCDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745641-B2 | Nitrogen-containing heterocyclic compound | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2010-06-29 | — | — | US | disclosed |
| US-20090054407-A1 | Nitrogen-containing heterocyclic compound | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054407-A1 | Nitrogen-containing heterocyclic compound | NR4A1, NR5A2, PRMT8 | CHEK1 3306/4885CYP2D6 217/4885PDE2A 2410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.