Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 3/20 | 0.67 |
| ▸ | FLT3 | P36888 | 4/20 | 0.60 |
| ▸ | MET | P08581 | 15/20 | 0.59 |
| ▸ | KDR | P35968 | 3/20 | 0.59 |
| ▸ | INSR | P06213 | 2/20 | 0.59 |
| ▸ | PLK4 | O00444 | 1/20 | 0.59 |
| ▸ | STK25 | O00506 | 1/20 | 0.59 |
| ▸ | CIT | O14578 | 1/20 | 0.59 |
| ▸ | AURKA | O14965 | 1/20 | 0.59 |
| ▸ | CHUK | O15111 | 1/20 | 0.59 |
| ▸ | MUSK | O15146 | 1/20 | 0.59 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.59 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.59 |
| ▸ | MAP3K13 | O43283 | 1/20 | 0.59 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.59 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.59 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.59 |
| ▸ | JAK2 | O60674 | 1/20 | 0.59 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.59 |
| ▸ | PAK3 | O75914 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25233374 | 0.94 | AXL (0.66) | AXLFLT3METKDRINSR | |
| SCHEMBL25278954 | 0.92 | AXL (0.62) | AXLFLT3METKDRINSR | |
| SCHEMBL1555923 | 0.85 | AXL (0.78) | AXLFLT3METKDRINSR | |
| SCHEMBL14742820 | 0.83 | AXL (0.81) | AXLFLT3METKDRINSR | |
| SCHEMBL30465532 | 0.83 | AXL (0.81) | AXLFLT3METKDRINSR | |
| SCHEMBL1591146 | 0.81 | AXL (0.71) | AXLFLT3METKDRINSR | |
| SCHEMBL6431273 | 0.81 | AXL (0.73) | AXLFLT3METKDRINSR | |
| SCHEMBL25719174 | 0.81 | AXL (0.73) | AXLFLT3METKDRINSR | |
| SCHEMBL30465529 | 0.80 | AXL (0.51) | AXLFLT3MET | |
| SCHEMBL14289180 | 0.80 | AXL (1.00) | AXLFLT3METKDRINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4448510-A1 | INHIBITORS OF MET KINASE | Kinnate Biopharma Inc. (US) | 2024-10-23 | — | — | EP | disclosed |
| WO-2023114809-A1 | INHIBITORS OF MET KINASE | KINNATE BIOPHARMA INC. (US) | 2023-06-22 | — | — | WO | disclosed |