Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 3/20 | 0.43 |
| ▸ | KDR | P35968 | 7/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 6/20 | 0.43 |
| ▸ | AXL | P30530 | 4/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 4/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 4/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | LYN | P07948 | 1/20 | 0.41 |
| ▸ | TEK | Q02763 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30465700 | 0.95 | FLT3 (0.44) | FGFR2KDRPDGFRAAXLKIT | |
| SCHEMBL30465793 | 0.94 | EGFR (0.44) | FGFR2KDRPDGFRAAXLKIT | |
| SCHEMBL25231641 | 0.94 | FGFR2 (0.42) | FGFR2KDRPDGFRAAXLKIT | |
| SCHEMBL25279725 | 0.94 | MET (0.41) | FGFR2KDRPDGFRAAXLKIT | |
| SCHEMBL25278653 | 0.93 | KDR (0.42) | FGFR2KDRPDGFRAAXLKIT | |
| SCHEMBL30465511 | 0.93 | MET (0.43) | FGFR2KDRPDGFRAAXLKIT | |
| SCHEMBL30465768 | 0.93 | FLT3 (0.44) | FGFR2KDRPDGFRAAXLKIT | |
| Hydrochloric Acid SCHEMBL25238287 | 0.93 | KDR (0.42) | FGFR2KDRPDGFRAAXLKIT | |
| SCHEMBL30465704 | 0.92 | MET (0.43) | FGFR2KDRPDGFRAAXLKIT | |
| SCHEMBL30465567 | 0.92 | RET (0.41) | FGFR2KDRPDGFRAAXLKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4448510-A1 | INHIBITORS OF MET KINASE | Kinnate Biopharma Inc. (US) | 2024-10-23 | — | — | EP | disclosed |
| WO-2023114809-A1 | INHIBITORS OF MET KINASE | KINNATE BIOPHARMA INC. (US) | 2023-06-22 | — | — | WO | disclosed |