Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 2/20 | 0.37 |
| ▸ | PRKCI | P41743 | 2/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.30 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19792317 | 1.00 | DYRK1A (0.40) | DYRK1ATNFRIPK1AXLPRKCI | |
| SCHEMBL1763343 | 0.85 | DYRK1A (0.44) | DYRK1ATNFRIPK1AXLPRKCI | |
| SCHEMBL12491288 | 0.80 | PRKCI (0.42) | DYRK1ATNFRIPK1AXLPRKCI | |
| SCHEMBL29197433 | 0.78 | DYRK1A (0.41) | DYRK1AAXLPRKCINUDT1AHR | |
| SCHEMBL30855430 | 0.78 | DYRK1A (0.41) | DYRK1AAXLPRKCINUDT1AHR | |
| SCHEMBL23912514 | 0.77 | PRKCI (0.40) | DYRK1AAXLPRKCIAHRCCR8 | |
| SCHEMBL31000802 | 0.77 | NUDT1 (0.37) | TNFRIPK1AXLPRKCINUDT1 | |
| SCHEMBL22509925 | 0.77 | NUDT1 (0.37) | DYRK1ATNFRIPK1AXLPRKCI | |
| SCHEMBL25285039 | 0.77 | NUDT1 (0.37) | TNFRIPK1AXLPRKCINUDT1 | |
| SCHEMBL18479114 | 0.77 | AXL (0.53) | DYRK1AAXLPRKCIAHRCCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4504716-A1 | COMPOUNDS AND METHODS OF TREATING CANCERS | Cullgen (Shanghai), Inc. (CN) | 2025-02-12 | — | — | EP | disclosed |
| CN-119156381-A | Compounds and methods for treating cancer | 上海睿跃生物科技有限公司 | 2024-12-17 | — | — | CN | disclosed |
| WO-2023193760-A1 | COMPOUNDS AND METHODS OF TREATING CANCERS | CULLGEN (SHANGHAI) , INC. (CN) | 2023-10-12 | — | — | WO | disclosed |
| WO-2023108536-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2023-06-22 | — | — | WO | disclosed |