Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28371117 | 1.00 | KDM4A (0.41) | KDM4AGLSL3MBTL1DYRK1APDPK1 | |
| SCHEMBL23874407 | 0.86 | KDM4A (0.41) | KDM4AGLSL3MBTL1DYRK1APDPK1 | |
| SCHEMBL30466622 | 0.86 | GAA (0.46) | KDM4AGLSHPGDMAPT | |
| SCHEMBL28366626 | 0.86 | GAA (0.46) | KDM4AGLSHPGDMAPT | |
| SCHEMBL30466623 | 0.86 | GAA (0.46) | KDM4AGLSHPGDMAPT | |
| SCHEMBL23857778 | 0.85 | GLS (0.41) | KDM4AGLSL3MBTL1DYRK1APDPK1 | |
| SCHEMBL23874457 | 0.84 | GLS (0.39) | KDM4AGLSL3MBTL1DYRK1APDPK1 | |
| SCHEMBL23874527 | 0.84 | AURKA (0.43) | KDM4AGLSDYRK1APARP1 | |
| SCHEMBL20511669 | 0.81 | HPGD (0.41) | L3MBTL1DYRK1APOLBMAPK1ATM | |
| SCHEMBL4159541 | 0.80 | HPGD (0.55) | KDM4AL3MBTL1POLBMAPK1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3601224-B1 | CHEMICAL COMPOUNDS AS ANTIBIOTICS | ANTABIO SAS (FR) | 2023-07-05 | — | — | EP | disclosed |