Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 8/20 | 0.53 |
| ▸ | RXRB | P28702 | 7/20 | 0.44 |
| ▸ | RXRA | P19793 | 6/20 | 0.44 |
| ▸ | RXRG | P48443 | 3/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20595534 | 1.00 | KIF11 (0.53) | KIF11RXRBRXRARXRGGABRA1 | |
| SCHEMBL20825774 | 0.92 | KIF11 (0.68) | KIF11RXRBRXRAGABRA1GABRG2 | |
| SCHEMBL30281941 | 0.86 | KIF11 (0.59) | KIF11GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL20825851 | 0.86 | KIF11 (0.59) | KIF11GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL24126349 | 0.85 | KIF11 (0.59) | KIF11RXRBRXRAGABRA1GABRG2 | |
| SCHEMBL30129678 | 0.85 | KIF11 (0.53) | KIF11RXRBRXRARXRG | |
| SCHEMBL23883587 | 0.85 | KIF11 (0.53) | KIF11RXRBRXRARXRG | |
| SCHEMBL31343934 | 0.83 | KIF11 (0.66) | KIF11GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL20595531 | 0.83 | KIF11 (0.39) | KIF11RXRBRXRARXRGGABRA1 | |
| SCHEMBL29152751 | 0.81 | KIF11 (0.53) | KIF11RXRBRXRARXRGGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3642250-B1 | BIARYL PHENOXY GROUP IV TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION | DOW GLOBAL TECHNOLOGIES LLC (US) | 2024-12-18 | — | — | EP | claimed |
| CN-110809586-B | Biaryl phenoxy group IV transition metal catalysts for olefin polymerization | 陶氏环球技术有限责任公司 | 2023-06-27 | — | — | CN | claimed |