Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 2/20 | 0.40 |
| ▸ | ERN1 | O75460 | 5/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24253045 | 1.00 | NQO2 (0.40) | NQO2ERN1ALOX15ALOX12APP | |
| SCHEMBL24252469 | 0.81 | NQO2 (0.40) | NQO2ERN1ALOX15ALOX12PDE10A | |
| SCHEMBL30467653 | 0.81 | NQO2 (0.40) | NQO2ERN1ALOX15ALOX12PDE10A | |
| SCHEMBL24252435 | 0.78 | NQO2 (0.35) | NQO2 | |
| SCHEMBL30467651 | 0.78 | NQO2 (0.35) | NQO2 | |
| SCHEMBL23589218 | 0.78 | CYP3A4 (0.38) | NQO2ALOX15ALOX12MEN1KMT2A | |
| SCHEMBL24478455 | 0.74 | NQO2 (0.40) | NQO2ERN1ALOX15ALOX12APP | |
| Hydrochloric Acid SCHEMBL29015516 | 0.73 | — | — | |
| SCHEMBL30626099 | 0.73 | ALDH1A1 (0.46) | NQO2ALOX15ALOX12PDE10AALDH1A1 | |
| Hydrochloric Acid SCHEMBL29665252 | 0.73 | NQO2 (0.39) | NQO2ERN1ALOX15ALOX12APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240109920-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | ANNEXON, INC. | 2024-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240109920-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | CFB, CFH, C9 | NQO2 279/4885ERN1 3015/4885ALOX15 106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.