Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.54 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 6/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.40 |
| ▸ | LCK | P06239 | 3/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19337104 | 1.00 | EGFR (0.54) | EGFRKDRMKNK2MKNK1LCK | |
| SCHEMBL19707904 | 0.89 | EGFR (0.43) | EGFRKDRMKNK2MKNK1 | |
| SCHEMBL28392219 | 0.89 | EGFR (0.46) | EGFRKDRMKNK2MKNK1LCK | |
| SCHEMBL20610525 | 0.89 | EGFR (0.46) | EGFRKDRMKNK2MKNK1CCNT1 | |
| SCHEMBL19337191 | 0.89 | EGFR (0.43) | EGFRKDRMKNK2MKNK1CCNT1 | |
| SCHEMBL21265492 | 0.88 | CCNT1 (0.46) | EGFRKDRMKNK2MKNK1LCK | |
| SCHEMBL30647338 | 0.88 | CCNT1 (0.46) | EGFRKDRMKNK2MKNK1LCK | |
| SCHEMBL19337070 | 0.87 | EGFR (0.43) | EGFRKDRMKNK2MKNK1CCNT1 | |
| SCHEMBL19089467 | 0.85 | KDR (0.44) | EGFRKDR | |
| SCHEMBL30930115 | 0.85 | KDR (0.43) | EGFRKDRMKNK2MKNK1CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111875585-B | Kinase inhibitors | 上海艾力斯医药科技股份有限公司 | 2023-06-23 | — | — | CN | disclosed |