Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | AOC2 | O75106 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1700214 | 1.00 | LMNA (0.51) | LMNAMAPTCA2CA1CA9 | |
| SCHEMBL1958870 | 0.88 | LMNA (0.47) | LMNAMAPTCA2CA1CA9 | |
| SCHEMBL1700221 | 0.87 | LMNA (0.49) | LMNAMAPTCA2CA1CA9 | |
| SCHEMBL523821 | 0.86 | LMNA (0.48) | LMNAMAPTCA2CA1CA9 | |
| SCHEMBL29482089 | 0.86 | LMNA (0.48) | LMNAMAPTCA2CA1CA9 | |
| SCHEMBL1700056 | 0.78 | LMNA (0.51) | LMNAMAPTCA2CA1CA9 | |
| SCHEMBL16037480 | 0.77 | MAPT (0.56) | LMNAMAPTPOLBMAPK1KMT2A | |
| SCHEMBL1700226 | 0.77 | LMNA (0.48) | LMNAMAPTCA2CA1CA9 | |
| SCHEMBL30467963 | 0.77 | LMNA (0.48) | LMNAMAPTCA2CA1CA9 | |
| SCHEMBL6112716 | 0.76 | LMNA (0.60) | LMNAMAPTCA2CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4218731-A2 | MELT-EXTRUDED SOLID DISPERSIONS CONTAINING AN APOPTOSIS-INDUCING AGENT | AbbVie Ireland Unlimited Company (IE) | 2023-08-02 | — | — | EP | disclosed |