SCHEMBL30468209

SCHEMBL30468209

CCCCCCCCCCCCN(CCCCCCCCCCCC)C(=O)N1C=Cc2ccccc2C1

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 6/20 0.46
P2RX1 P51575 1/20 0.42
P2RX3 P56373 1/20 0.42
P2RX4 Q99571 1/20 0.42
HDAC3 O15379 1/20 0.41
NAMPT P43490 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30468287 0.88 HDAC3 (0.40) TACR1P2RX1P2RX3P2RX4HDAC3
SCHEMBL4836475 0.80 HDAC3 (0.46) TACR1HDAC3NAMPT
SCHEMBL29038577 0.78 NAMPT (0.62) HDAC3NAMPT
SCHEMBL3912608 0.77 HDAC3 (0.40) P2RX1P2RX3P2RX4HDAC3NAMPT
SCHEMBL324190 0.74 BCHE (0.44) HDAC3NAMPT
SCHEMBL4553750 0.74 HTT (0.47) P2RX1P2RX3P2RX4HDAC3NAMPT
SCHEMBL6168375 0.72 HSD17B3 (0.49) P2RX1P2RX3P2RX4HDAC3NAMPT
SCHEMBL15056964 0.72 HDAC3 (0.41) HDAC3NAMPT
SCHEMBL29493251 0.72 HDAC3 (0.41) HDAC3NAMPT
SCHEMBL16268687 0.71 NAMPT (0.47) HDAC3NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116479237-A Extractant, preparation method and application thereof 中国科学院过程工程研究所 2023-07-25 CN disclosed