Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 7/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 7/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27872842 | 0.84 | HDAC3 (0.43) | HSD17B3NOTUMHDAC3MEN1MAPT | |
| SCHEMBL29950507 | 0.84 | HDAC3 (0.43) | HSD17B3NOTUMHDAC3MEN1MAPT | |
| SCHEMBL304994 | 0.84 | HDAC3 (0.43) | HSD17B3NOTUMHDAC3MEN1MAPT | |
| SCHEMBL305168 | 0.82 | HDAC3 (0.43) | HSD17B3NOTUMHDAC3MEN1MAPT | |
| SCHEMBL4425411 | 0.82 | HDAC3 (0.43) | HSD17B3NOTUMHDAC3MEN1MAPT | |
| Hydrochloric Acid SCHEMBL7007436 | 0.82 | HDAC3 (0.43) | HSD17B3NOTUMHDAC3MEN1MAPT | |
| SCHEMBL30014867 | 0.82 | HDAC3 (0.43) | HSD17B3NOTUMHDAC3MEN1MAPT | |
| SCHEMBL29493257 | 0.82 | HDAC3 (0.43) | HSD17B3NOTUMHDAC3MEN1MAPT | |
| SCHEMBL4553385 | 0.81 | MEN1 (0.45) | HSD17B3NOTUMHDAC3MEN1KMT2A | |
| SCHEMBL4553750 | 0.81 | HTT (0.47) | HSD17B3NOTUMHDAC3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532141-A1 | 2-PYRROLIDIN-2-YL- 1,3,4]-OXADIAZOLE DERIVATIVES AND THE USE OF THE SAME AS ANTIDEPRESSANTS | Grünenthal GmbH (DE) | 2005-05-25 | — | — | EP | claimed |
| WO-2004024725-A1 | 2-PYRROLIDIN-2-YL-[1,3,4]-OXADIAZOLE DERIVATIVES AND THE USE OF THE SAME AS ANTIDEPRESSANTS | Grünenthal GmbH (DE) | 2004-03-25 | — | — | WO | claimed |
| US-20230322815-A1 | NOVEL COMPOUNDS AND THERAPEUTIC USES THEREOF | UNIVERSITY OF HUDDERSFIELD (GB) | 2023-10-12 | — | — | US | disclosed |
| EP-4196226-A1 | NOVEL COMPOUNDS AND THERAPEUTIC USES THEREOF | University Of Huddersfield (GB) | 2023-06-21 | — | — | EP | disclosed |
| WO-2022034313-A1 | NOVEL COMPOUNDS AND THERAPEUTIC USES THEREOF | UNIVERSITY OF HUDDERSFIELD (GB) | 2022-02-17 | — | — | WO | disclosed |
| CN-102417523-B | Preparation and catalytic application of nitrogen heterocyclic ligand transition metal complex | ZHONGSHAN ENANTIOTECH Corp.,Ltd. (CN) | 2014-10-08 | — | — | CN | disclosed |
| US-8779134-B1 | Six-coordinated ruthenium complex | NATIONAL TSING HUA UNIVERSITY (TW) | 2014-07-15 | — | — | US | disclosed |
| CN-102417523-A | Nitrogen heterocyclic ligand transition metal complex, preparation and catalytic application thereof | ZHONGSHAN YIANTAI MEDICAL TECHNOLOGY CO LTD | 2012-04-18 | — | — | CN | disclosed |
| EP-1532141-A1 | 2-PYRROLIDIN-2-YL- 1,3,4]-OXADIAZOLE DERIVATIVES AND THE USE OF THE SAME AS ANTIDEPRESSANTS | Grünenthal GmbH (DE) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004024725-A1 | 2-PYRROLIDIN-2-YL-[1,3,4]-OXADIAZOLE DERIVATIVES AND THE USE OF THE SAME AS ANTIDEPRESSANTS | Grünenthal GmbH (DE) | 2004-03-25 | — | — | WO | disclosed |
| EP-0828754-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER INC. (US) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996038471-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER INC. (US) | 1996-12-05 | — | — | WO | disclosed |
| WO-1996035713-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER, INC. (US) | 1996-11-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230322815-A1 | NOVEL COMPOUNDS AND THERAPEUTIC USES THEREOF | BRCA1, TPX2, XPA | HSD17B3 2306/4885NOTUM 4794/4885HDAC3 3412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.