Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | VEGFA | P15692 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30468254 | 0.94 | SUCNR1 (0.44) | PCSK9MCHR1MAPK8KDM4EACKR3 | |
| SCHEMBL30468301 | 0.93 | SMN1; SMN2 (0.45) | SMN1; SMN2PCSK9MAPK8KDM4EALDH1A1 | |
| SCHEMBL30468230 | 0.92 | MAPK8 (0.43) | PCSK9MAPK8ACKR3MEN1KMT2A | |
| SCHEMBL30468247 | 0.92 | SUCNR1 (0.44) | PCSK9MCHR1MAPK8MEN1KMT2A | |
| SCHEMBL30468235 | 0.92 | BACE1 (0.46) | SMN1; SMN2PCSK9MAPK8SUCNR1BACE1 | |
| SCHEMBL30468222 | 0.92 | NPC1 (0.45) | PCSK9MCHR1ACKR3KMT2ARAB9A | |
| SCHEMBL30468303 | 0.91 | PCSK9 (0.43) | PCSK9MAPK8ACKR3SUCNR1BACE1 | |
| SCHEMBL30468284 | 0.90 | MAPK8 (0.42) | NPSR1HTTVEGFAEGLN1MAPK8 | |
| SCHEMBL30468296 | 0.90 | PCSK9 (0.43) | HTTPCSK9KDM4EALDH1A1MEN1 | |
| SCHEMBL30468300 | 0.89 | MAPK8 (0.46) | MAPK8ALDH1A1ACKR3CHRM1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613735-B1 | NOVEL SIRT 1 ACTIVATOR AND MEDICINAL USE THEREOF | NAT UNIV PUSAN IND UNIV COOP FOUND (KR) | 2023-04-12 | — | — | EP | disclosed |