Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 3/20 | 0.43 |
| ▸ | MGLL | Q99685 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30468240 | 0.93 | ALDH1A1 (0.43) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL30468254 | 0.91 | SUCNR1 (0.44) | PCSK9FAAHDRD4KDM4E | |
| SCHEMBL30468301 | 0.90 | SMN1; SMN2 (0.45) | PCSK9DRD4ALDH1A1LMNAMAPT | |
| SCHEMBL30468290 | 0.90 | NPSR1 (0.46) | PCSK9DRD4ALDH1A1KDM4EMEN1 | |
| SCHEMBL30468235 | 0.90 | BACE1 (0.46) | PCSK9DRD4 | |
| SCHEMBL30468222 | 0.89 | NPC1 (0.45) | PCSK9FAAHDRD4KMT2A | |
| SCHEMBL20541643 | 0.89 | ALDH1A1 (0.46) | CCR5MGLLFAAHDRD4ALDH1A1 | |
| SCHEMBL30468303 | 0.88 | PCSK9 (0.43) | PCSK9 | |
| SCHEMBL30468230 | 0.87 | MAPK8 (0.43) | PCSK9FAAHACHEMEN1KMT2A | |
| SCHEMBL30468314 | 0.86 | SUCNR1 (0.45) | PCSK9FAAHDRD4ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613735-B1 | NOVEL SIRT 1 ACTIVATOR AND MEDICINAL USE THEREOF | NAT UNIV PUSAN IND UNIV COOP FOUND (KR) | 2023-04-12 | — | — | EP | disclosed |