Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 7/20 | 0.47 |
| ▸ | BTK | Q06187 | 7/20 | 0.45 |
| ▸ | PTK2B | Q14289 | 5/20 | 0.45 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.43 |
| ▸ | AXL | P30530 | 2/20 | 0.43 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.43 |
| ▸ | PLK4 | O00444 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | STK16 | O75716 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | PAK4 | O96013 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | PRKCG | P05129 | 1/20 | 0.43 |
| ▸ | INSR | P06213 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29051792 | 0.99 | PTK2 (0.47) | PTK2BTKPTK2BSTK17AAXL | |
| SCHEMBL30468470 | 0.91 | PTK2 (0.47) | PTK2BTKPTK2BSTK17AAXL | |
| Hydrochloric Acid SCHEMBL29051677 | 0.91 | PTK2 (0.46) | PTK2BTKPTK2BSTK17AAXL | |
| SCHEMBL30468504 | 0.89 | STK17A (0.45) | PTK2BTKSTK17AAXLCAMK2D | |
| Hydrochloric Acid SCHEMBL29051920 | 0.88 | STK17A (0.44) | PTK2BTKSTK17AAXLCAMK2D | |
| SCHEMBL30468452 | 0.84 | PTK2 (0.59) | PTK2BTKPTK2BSTK17AAXL | |
| Hydrochloric Acid SCHEMBL29051817 | 0.84 | PTK2 (0.58) | PTK2BTKPTK2BSTK17AAXL | |
| Hydrochloric Acid SCHEMBL29051798 | 0.83 | PTK2 (0.47) | PTK2BTKPTK2BSTK17AAXL | |
| SCHEMBL30468427 | 0.80 | PTK2 (0.45) | PTK2AXLCAMK2DWEE1TYRO3 | |
| Hydrochloric Acid SCHEMBL29051773 | 0.79 | PTK2 (0.44) | PTK2AXLCAMK2DWEE1TYRO3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332910-A | 2-aminopyrimidine derivatives as kinase inhibitors, preparation and use thereof | 江苏威凯尔医药科技有限公司 | 2023-06-27 | — | — | CN | disclosed |