Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 3/20 | 0.37 |
| ▸ | S100A4 | P26447 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2385989 | 1.00 | ALDH1A1 (0.47) | ALDH1A1HPGDVCAM1CYP1A2POLB | |
| SCHEMBL30648694 | 0.87 | ALDH1A1 (0.47) | ALDH1A1HPGDVCAM1CYP1A2POLB | |
| SCHEMBL1817832 | 0.87 | ALDH1A1 (0.47) | ALDH1A1HPGDVCAM1CYP1A2POLB | |
| SCHEMBL10712226 | 0.81 | ALDH1A1 (0.62) | ALDH1A1HPGDVCAM1CYP1A2TDP1 | |
| SCHEMBL30279931 | 0.80 | ALDH1A1 (0.55) | ALDH1A1HPGDVCAM1CYP1A2TDP1 | |
| SCHEMBL7880816 | 0.80 | ALDH1A1 (0.47) | ALDH1A1HPGDVCAM1CYP1A2POLB | |
| SCHEMBL29780594 | 0.80 | ALDH1A1 (0.47) | ALDH1A1HPGDVCAM1CYP1A2TDP1 | |
| SCHEMBL2817314 | 0.80 | ALDH1A1 (0.55) | ALDH1A1HPGDVCAM1CYP1A2TDP1 | |
| SCHEMBL30127086 | 0.80 | HSD17B10 (0.55) | ALDH1A1HPGDVCAM1CYP1A2TDP1 | |
| SCHEMBL2815195 | 0.80 | ALDH1A1 (0.47) | ALDH1A1HPGDVCAM1CYP1A2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054368-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | NICO THERAPEUTICS, INC. (US) | 2025-03-13 | — | — | WO | disclosed |
| CN-116332910-A | 2-aminopyrimidine derivatives as kinase inhibitors, preparation and use thereof | 江苏威凯尔医药科技有限公司 | 2023-06-27 | — | — | CN | disclosed |