Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 4/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.36 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | VNN1 | O95497 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 4/20 | 0.32 |
| ▸ | PRKCB | P05771 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.31 |
| ▸ | BTD | P43251 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1234120 | 0.88 | EGLN1 (0.39) | PRKDCEGLN1IDO1SMN1; SMN2 | |
| SCHEMBL30988531 | 0.77 | CALCRL (0.38) | PRKDCEGLN1CALCRLL3MBTL1VNN1 | |
| SCHEMBL31368769 | 0.75 | PRKDC (0.39) | PRKDCEGLN1CALCRLALDH1A1SMN1; SMN2 | |
| SCHEMBL30276209 | 0.71 | PRKDC (0.43) | PRKDCEGLN1L3MBTL1ALDH1A1GAA | |
| SCHEMBL30496839 | 0.71 | EGLN1 (0.42) | PRKDCEGLN1IDO1 | |
| SCHEMBL30276171 | 0.70 | PRKDC (0.43) | PRKDCEGLN1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31369000 | 0.70 | EGLN1 (0.41) | PRKDCEGLN1SMN1; SMN2 | |
| SCHEMBL30276207 | 0.70 | PRKDC (0.43) | PRKDCEGLN1L3MBTL1ALDH1A1 | |
| SCHEMBL30276155 | 0.69 | PRKDC (0.42) | PRKDCEGLN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL38662097 | 0.64 | SLC6A4 (0.44) | EGLN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227089-B | Substituted 6-azabenzimidazole compounds as HPK1 inhibitors | 吉利德科学公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-116731016-A | Tricyclic heterocyclic compounds as IAP antagonists | 苏州亚盛药业有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-110769821-B | Spiro indolines as IL-17 modulators | UCB生物制药有限责任公司 | 2023-07-07 | — | — | CN | disclosed |