Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 6/20 | 0.62 |
| ▸ | CTSK | P43235 | 5/20 | 0.62 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
| ▸ | MDM4 | O15151 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201737 | 0.93 | CTSS (0.67) | CTSSCTSKCTSLCTSBTSHR | |
| SCHEMBL22191069 | 0.93 | CTSS (0.67) | CTSSCTSKCTSLCTSBTSHR | |
| SCHEMBL22191071 | 0.93 | CTSS (0.67) | CTSSCTSKCTSLCTSBTSHR | |
| SCHEMBL29031984 | 0.90 | CTSS (0.63) | CTSSCTSKCTSLCTSBKLK5 | |
| SCHEMBL29031987 | 0.90 | CTSS (0.63) | CTSSCTSKCTSLCTSBKLK5 | |
| SCHEMBL29586741 | 0.89 | CTSS (0.65) | CTSSCTSKCTSLCTSBTSHR | |
| SCHEMBL2574440 | 0.88 | CTSS (0.66) | CTSSCTSKCTSLCTSBTSHR | |
| SCHEMBL539575 | 0.88 | CTSS (0.66) | CTSSCTSKCTSLCTSBTSHR | |
| SCHEMBL539574 | 0.88 | CTSS (0.66) | CTSSCTSKCTSLCTSBTSHR | |
| SCHEMBL30374091 | 0.88 | CTSS (0.66) | CTSSCTSKCTSLCTSBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112940071-B | Method for realizing alkynyl functionalization of cysteine and polypeptide thereof by utilizing microchannel reactor | 南京工业大学 | 2023-06-23 | — | — | CN | disclosed |