Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 20/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30468810 | 0.95 | GLP1R (0.45) | GLP1R | |
| SCHEMBL30468806 | 0.88 | GPR119 (0.46) | GLP1R | |
| SCHEMBL30468784 | 0.87 | GPR119 (0.46) | GLP1R | |
| SCHEMBL25282554 | 0.87 | GLP1R (0.51) | GLP1R | |
| SCHEMBL25282553 | 0.87 | GLP1R (0.51) | GLP1R | |
| SCHEMBL29668681 | 0.87 | GLP1R (0.58) | GLP1R | |
| SCHEMBL20266522 | 0.87 | GLP1R (0.58) | GLP1R | |
| SCHEMBL30468788 | 0.86 | GPR119 (0.44) | GLP1R | |
| SCHEMBL24485500 | 0.85 | GLP1R (0.55) | GLP1R | |
| SCHEMBL28801287 | 0.85 | GLP1R (0.55) | GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250066338-A1 | CERTAIN 3-AZABICYCLO[3.1.0]HEXANES AS GLP-1 RECEPTOR MODULATORS | ASTRAZENECA AB (SE) | 2025-02-27 | — | — | US | disclosed |
| WO-2023111144-A1 | CERTAIN 3-AZABICYCLO[3.1.0]HEXANES AS GLP-1 RECEPTOR MODULATORS | ASTRAZENECA AB (SE) | 2023-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250066338-A1 | CERTAIN 3-AZABICYCLO[3.1.0]HEXANES AS GLP-1 RECEPTOR MODULATORS | GLP1R, GPR119, GIPR | GLP1R 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.