SCHEMBL30468902

SCHEMBL30468902

O=C(O)C1CC1c1ccc(Cl)cc1Cl

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
SLC9A1 P19634 2/20 0.49
HTR2A P28223 1/20 0.49
HTR2C P28335 1/20 0.49
HTR2B P41595 1/20 0.49
DPP4 P27487 5/20 0.48
MAPK1 P28482 1/20 0.46
TSHR P16473 2/20 0.43
CASP1 P29466 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
CYP2C19 P33261 1/20 0.42
KMO O15229 2/20 0.41
GAA P10253 1/20 0.41
AGTR1 P30556 1/20 0.41
FFAR1 O14842 1/20 0.41
NOTUM Q6P988 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17103896 1.00 MEN1 (0.50) MEN1KMT2ASLC9A1HTR2AHTR2C
SCHEMBL17103897 1.00 MEN1 (0.50) MEN1KMT2ASLC9A1HTR2AHTR2C
SCHEMBL24738015 0.86 SLC9A1 (0.64) MEN1KMT2ASLC9A1MAPK1TSHR
SCHEMBL29302263 0.86 SLC9A1 (0.64) MEN1KMT2ASLC9A1MAPK1TSHR
SCHEMBL1586035 0.85 DPP4 (0.54) MEN1KMT2ASLC9A1HTR2AHTR2C
SCHEMBL11902519 0.83 HTR2A (0.51) MEN1KMT2ASLC9A1HTR2AHTR2C
SCHEMBL10288279 0.83 HTR2A (0.51) SLC9A1HTR2AHTR2CHTR2BKMO
SCHEMBL24845071 0.83 FFAR1 (0.48) MEN1KMT2ASLC9A1DPP4KMO
SCHEMBL10288453 0.83 HTR2A (0.51) SLC9A1HTR2AHTR2CHTR2BKMO
SCHEMBL2137772 0.83 HTR2A (0.51) SLC9A1HTR2AHTR2CHTR2BKMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116396356-A Functionalized polypeptide derivative as inhibiting virus main protease, preparation method and application thereof 深圳微芯生物科技股份有限公司 2023-07-07 CN disclosed