Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dioxane SCHEMBL6854158 | 0.96 | TTR (0.46) | TTRSMN1; SMN2USP2ALDH1A1RECQL | |
| Dioxane SCHEMBL1476307 | 0.96 | TTR (0.46) | TTRSMN1; SMN2USP2ALDH1A1RECQL | |
| Tert-Butanol SCHEMBL18420144 | 0.96 | — | — | |
| Dioxane SCHEMBL1277036 | 0.88 | TTR (0.46) | TTRSMN1; SMN2USP2ALDH1A1RECQL | |
| Dioxane SCHEMBL7231219 | 0.87 | SMN1; SMN2 (0.46) | TTRSMN1; SMN2USP2ALDH1A1RECQL | |
| Tetrahydrofuran SCHEMBL711363 | 0.85 | ALDH1A1 (0.57) | TTRSMN1; SMN2USP2ALDH1A1RECQL | |
| Tert-Butanol SCHEMBL8113356 | 0.82 | ALDH1A1 (0.53) | TTRALDH1A1RECQL | |
| Tetrahydrofuran SCHEMBL11173089 | 0.82 | ALDH1A1 (0.53) | TTRALDH1A1RECQL | |
| Tetrahydrofuran SCHEMBL3464478 | 0.82 | ALDH1A1 (0.53) | TTRALDH1A1RECQL | |
| Tetrahydrofuran SCHEMBL10597993 | 0.82 | ALDH1A1 (0.53) | TTRALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115521298-A | Preparation method of brexpiprazole | 江苏慧聚药业股份有限公司 | 2022-12-27 | — | — | CN | claimed |
| US-12029816-B2 | Compositions and methods of making brittle-matrix particles through blister pack freezing | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2024-07-09 | — | — | US | disclosed |
| CN-117820816-A | Flame-retardant and easily-degradable epoxy resin precursor, cured product, preparation method and application | 中国科学院宁波材料技术与工程研究所 | 2024-04-05 | — | — | CN | disclosed |
| CN-115521298-A | Preparation method of brexpiprazole | 江苏慧聚药业股份有限公司 | 2022-12-27 | — | — | CN | disclosed |
| US-11364197-B2 | Compositions and methods of making brittle-matrix particles through blister pack freezing | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2022-06-21 | — | — | US | disclosed |
| US-20210007971-A1 | COMPOSITIONS AND METHODS OF MAKING BRITTLE-MATRIX PARTICLES THROUGH BLISTER PACK FREEZING | UNIV TEXAS (US) | 2021-01-14 | — | — | US | disclosed |
| US-10660850-B2 | Compositions and methods of making brittle-matrix particles through blister pack freezing | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2020-05-26 | — | — | US | disclosed |
| US-20200069572-A1 | COMPOSITIONS AND METHODS OF MAKING BRITTLE-MATRIX PARTICLES THROUGH BLISTER PACK FREEZING | UNIV TEXAS (US) | 2020-03-05 | — | — | US | disclosed |
| US-10434062-B2 | Compositions and methods of making brittle-matrix particles through blister pack freezing | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2019-10-08 | — | — | US | disclosed |
| US-20190117557-A1 | COMPOSITIONS AND METHODS OF MAKING BRITTLE-MATRIX PARTICLES THROUGH BLISTER PACK FREEZING | UNIV TEXAS (US) | 2019-04-25 | — | — | US | disclosed |
| WO-2009103035-A2 | TEMPLATED OPEN FLOCS OF ANISOTROPIC PARTICLES FOR ENHANCED PULMONARY DELIVERY | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2009-08-20 | — | — | WO | disclosed |
| US-20090208582-A1 | Templated Open Flocs of Anisotropic Particles for Enhanced Pulmonary Delivery | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2009-08-20 | — | — | US | disclosed |
| EP-1942892-A1 | SOLID DISPERSIONS OF OPIOID ANTAGONISTS | Adolor Corporation (US) | 2008-07-16 | — | — | EP | disclosed |
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | disclosed |
| WO-2007044713-A1 | SOLID DISPERSIONS OF OPIOID ANTAGONISTS | ADOLOR CORPORATION (US) | 2007-04-19 | — | — | WO | disclosed |
| US-7138420-B2 | Substituted benzimidazole compounds | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2006-11-21 | — | — | US | disclosed |
| US-20050203158-A1 | Substituted benzimidazole compounds | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2005-09-15 | — | — | US | disclosed |
| EP-1529046-A1 | SUBSTITUTED BENZIMIDAZOLE COMPOUNDS | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2005-05-11 | — | — | EP | disclosed |
| WO-2004014905-A1 | SUBSTITUTED BENZIMIDAZOLE COMPOUNDS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2004-02-19 | — | — | WO | disclosed |
| US-6114526-A | REACTING AN AMINO DERIVATIVE WITH A HETEROCYCLIC DIONE COMPOUND TO FORM AN ANTIDIABETIC AGENT | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203158-A1 | Substituted benzimidazole compounds | ITK, BLK, SBK1 | TTR 4741/4885SMN1; SMN2 4120/4885USP2 4017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.