Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.66 |
| ▸ | MAPT | P10636 | 7/20 | 0.66 |
| ▸ | NOX1 | Q9Y5S8 | 4/20 | 0.65 |
| ▸ | TP53 | P04637 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | CNR1 | P21554 | 11/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20557638 | 1.00 | MEN1 (0.66) | MEN1KMT2AMAPTNOX1TP53 | |
| SCHEMBL10221479 | 0.87 | MEN1 (0.73) | MEN1KMT2AMAPTNOX1TP53 | |
| SCHEMBL17932839 | 0.85 | MEN1 (0.81) | MEN1KMT2AMAPTNOX1TP53 | |
| SCHEMBL10384848 | 0.85 | KCNK3 (0.58) | MEN1KMT2AMAPTNOX1TP53 | |
| SCHEMBL30469233 | 0.84 | MAPT (0.75) | MEN1KMT2AMAPTNOX1TP53 | |
| SCHEMBL4921262 | 0.84 | MAPT (0.75) | MEN1KMT2AMAPTNOX1TP53 | |
| SCHEMBL11659301 | 0.81 | MEN1 (0.58) | MEN1KMT2AMAPTNOX1TP53 | |
| SCHEMBL697935 | 0.79 | ALDH1A1 (0.58) | MEN1KMT2AMAPTNOX1TP53 | |
| SCHEMBL29594409 | 0.79 | ALDH1A1 (0.58) | MEN1KMT2AMAPTNOX1TP53 | |
| SCHEMBL11438420 | 0.79 | MEN1 (0.60) | MEN1KMT2AMAPTTP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283668-A | Diaryl ureas as CB1 allosteric modulators | 研究三角协会 | 2023-06-23 | — | — | CN | claimed |