Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | PGR | P06401 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20557899 | 1.00 | TSHR (0.51) | TSHRACHELMNASMN1; SMN2PGR | |
| SCHEMBL6738366 | 0.80 | TSHR (0.76) | TSHRACHELMNASMN1; SMN2PGR | |
| Iodide SCHEMBL28598177 | 0.78 | TSHR (0.73) | TSHRACHELMNASMN1; SMN2PGR | |
| SCHEMBL28471286 | 0.78 | TSHR (0.73) | TSHRACHELMNASMN1; SMN2PGR | |
| SCHEMBL11392461 | 0.78 | TSHR (0.73) | TSHRACHELMNASMN1; SMN2PGR | |
| SCHEMBL11392466 | 0.78 | TSHR (0.73) | TSHRACHELMNASMN1; SMN2PGR | |
| Iodide SCHEMBL30804629 | 0.78 | TSHR (0.73) | TSHRACHELMNASMN1; SMN2PGR | |
| SCHEMBL12360611 | 0.78 | TSHR (0.78) | TSHRACHELMNASMN1; SMN2PGR | |
| SCHEMBL1036939 | 0.76 | TSHR (0.63) | TSHRACHELMNAPGRMAPT | |
| SCHEMBL29526232 | 0.75 | TSHR (0.67) | TSHRACHELMNASMN1; SMN2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283668-A | Diaryl ureas as CB1 allosteric modulators | 研究三角协会 | 2023-06-23 | — | — | CN | disclosed |