Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 3/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.47 |
| ▸ | AXL | P30530 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20557309 | 1.00 | AHR (0.61) | AHRMAOACYP3A4TSHRCYP1B1 | |
| SCHEMBL11343706 | 0.85 | MAOA (0.56) | AHRMAOACYP3A4TSHRMAP4K4 | |
| SCHEMBL16545009 | 0.82 | MAOA (0.52) | MAOACYP3A4TSHRMAP4K4CA12 | |
| SCHEMBL18152405 | 0.82 | MAOA (0.52) | MAOACYP3A4TSHRMAP4K4CA12 | |
| SCHEMBL31131353 | 0.81 | MAOA (0.84) | MAOACYP3A4MAP4K4CA12CA1 | |
| SCHEMBL29561461 | 0.81 | MAOA (0.84) | MAOACYP3A4MAP4K4CA12CA1 | |
| SCHEMBL29394565 | 0.81 | MAOA (0.84) | MAOACYP3A4MAP4K4CA12CA1 | |
| SCHEMBL19446666 | 0.81 | MAOA (0.84) | MAOACYP3A4MAP4K4CA12CA1 | |
| SCHEMBL311194 | 0.81 | MAOA (0.84) | MAOACYP3A4MAP4K4CA12CA1 | |
| SCHEMBL29403794 | 0.81 | MAOA (0.83) | MAOACYP3A4MAP4K4CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283668-A | Diaryl ureas as CB1 allosteric modulators | 研究三角协会 | 2023-06-23 | — | — | CN | disclosed |