Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 3/20 | 0.57 |
| ▸ | CA1 | P00915 | 3/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.57 |
| ▸ | CA7 | P43166 | 3/20 | 0.57 |
| ▸ | CA9 | Q16790 | 3/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL670450 | 1.00 | HSD17B2 (0.59) | HSD17B2CA12CA1CA2CA7 | |
| SCHEMBL10958234 | 0.88 | NOTUM (0.56) | HSD17B2CA12CA1CA2CA7 | |
| SCHEMBL1011945 | 0.88 | HSD17B2 (0.61) | HSD17B2CA12CA1CA2CA7 | |
| SCHEMBL1630042 | 0.87 | HSD17B2 (0.57) | HSD17B2CA12CA1CA2CA7 | |
| SCHEMBL10945118 | 0.86 | HSD17B2 (0.73) | HSD17B2CA12CA1CA2CA7 | |
| SCHEMBL12493300 | 0.86 | TAS1R3 (0.60) | HSD17B2CA12CA1CA2CA7 | |
| SCHEMBL29776617 | 0.85 | HSD17B2 (0.55) | HSD17B2CA12CA1CA2CA7 | |
| SCHEMBL7715844 | 0.85 | HSD17B2 (0.77) | HSD17B2CA12CA1CA2CA7 | |
| SCHEMBL12126791 | 0.85 | HSD17B2 (0.55) | HSD17B2CA12CA1CA2CA7 | |
| SCHEMBL18652101 | 0.84 | CREBBP (0.63) | CYP3A4TSHRALDH1A1MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116348464-A | Benzimidazolone GLP-1 receptor agonists and uses thereof | 杭州中美华东制药有限公司 | 2023-06-27 | — | — | CN | disclosed |