Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.31 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.30 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24366391 | 1.00 | GPR119 (0.32) | GPR119SLC6A2SLC6A4SLC6A3USP30 | |
| SCHEMBL30886357 | 0.84 | CA12 (0.35) | GPR119 | |
| SCHEMBL24366758 | 0.84 | CA12 (0.35) | GPR119 | |
| SCHEMBL24364324 | 0.84 | CA12 (0.35) | GPR119 | |
| SCHEMBL29477413 | 0.84 | CA12 (0.35) | GPR119 | |
| SCHEMBL25322297 | 0.82 | NR1H2 (0.38) | SLC6A4SLC6A3USP30KDM1A | |
| SCHEMBL31578394 | 0.82 | NR1H2 (0.38) | SLC6A4SLC6A3USP30KDM1A | |
| SCHEMBL25322302 | 0.82 | NR1H2 (0.38) | SLC6A4SLC6A3USP30KDM1A | |
| SCHEMBL31136486 | 0.81 | NPC1 (0.39) | — | |
| SCHEMBL24363778 | 0.81 | NPC1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4188920-A1 | PIPERIDIN-1-YL-N-PYRYDINE-3-YL-2-OXOACETAMIDE DERIVATIVES USEFUL FOR THE TREATMENT OF MTAP-DEFICIENT AND/OR MTA-ACCUMULATING CANCERS | Tango Therapeutics, Inc. (US) | 2023-06-07 | — | — | EP | disclosed |