⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29338266 | 0.88 | — | — | |
| SCHEMBL6232352 | 0.70 | RAB9A (0.31) | — | |
| SCHEMBL29338491 | 0.67 | PRMT5 (0.34) | — | |
| SCHEMBL24233870 | 0.63 | — | — | |
| Water SCHEMBL10621554 | 0.61 | GAA (0.31) | — | |
| SCHEMBL1762422 | 0.60 | — | — | |
| SCHEMBL24233905 | 0.60 | — | — | |
| Hydrochloric Acid SCHEMBL10660266 | 0.60 | GAA (0.30) | — | |
| SCHEMBL1119401 | 0.59 | — | — | |
| SCHEMBL8228517 | 0.59 | TDP1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078117-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS INC (US) | 2026-03-19 | — | — | US | disclosed |
| EP-4188920-A1 | PIPERIDIN-1-YL-N-PYRYDINE-3-YL-2-OXOACETAMIDE DERIVATIVES USEFUL FOR THE TREATMENT OF MTAP-DEFICIENT AND/OR MTA-ACCUMULATING CANCERS | Tango Therapeutics, Inc. (US) | 2023-06-07 | — | — | EP | disclosed |