Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.53 |
| ▸ | IP6K1 | Q92551 | 12/20 | 0.51 |
| ▸ | OTUD7B | Q6GQQ9 | 5/20 | 0.43 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.41 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20721854 | 0.76 | OTUD7B (0.62) | BACE1IP6K1OTUD7BPDK2 | |
| SCHEMBL12548174 | 0.74 | IP6K1 (0.56) | BACE1IP6K1IP6K3IP6K2 | |
| SCHEMBL28940555 | 0.74 | BACE1 (0.63) | BACE1 | |
| SCHEMBL19411580 | 0.74 | BACE1 (0.63) | BACE1 | |
| SCHEMBL26225756 | 0.74 | BACE1 (0.58) | BACE1 | |
| SCHEMBL26237932 | 0.74 | BACE1 (0.58) | BACE1IP6K1 | |
| Hydrochloric Acid SCHEMBL1949327 | 0.73 | IP6K1 (0.55) | BACE1IP6K1IP6K3IP6K2 | |
| SCHEMBL29655503 | 0.70 | BACE1 (1.00) | BACE1PDK2 | |
| SCHEMBL251170 | 0.70 | BACE1 (1.00) | BACE1PDK2 | |
| SCHEMBL25756131 | 0.70 | BACE1 (1.00) | BACE1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109926-A1 | SPIROOXINDOLE COMPOUND AND USE THEREOF IN PREPARATION OF PROTEASE INHIBITOR AS ANTIVIRAL DRUG | 南京药石科技股份有限公司 | 2023-06-22 | — | — | WO | disclosed |