SCHEMBL30474396

SCHEMBL30474396

COC(Cc1ccccc1)(OC)C(C)=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
HIF1A Q16665 1/20 0.46
RECQL P46063 1/20 0.44
CYP2C9 P11712 2/20 0.44
CYP2C19 P33261 2/20 0.44
CYP3A4 P08684 1/20 0.44
PTPN2 P17706 1/20 0.41
PTPN1 P18031 1/20 0.41
PTPRA P18433 1/20 0.41
PTPRB P23467 1/20 0.41
SLC6A2 P23975 1/20 0.41
TAAR1 Q96RJ0 1/20 0.41
PPARG P37231 1/20 0.41
PPARA Q07869 1/20 0.41
MMP8 P22894 1/20 0.41
LMNA P02545 1/20 0.40
FDPS P14324 1/20 0.40
CYP1A2 P05177 1/20 0.39
NPC1 O15118 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30503782 0.98 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2HIF1ARECQLCYP2C9
SCHEMBL2678813 0.86 SMN1; SMN2 (0.52) ALDH1A1SMN1; SMN2HIF1ARECQLCYP2C9
SCHEMBL27457092 0.82 ALDH1A1 (0.47) ALDH1A1SMN1; SMN2HIF1ARECQLCYP2C9
SCHEMBL28536864 0.81 CES1 (0.51) ALDH1A1SMN1; SMN2HIF1ARECQLPTPN2
SCHEMBL4824469 0.80 SMN1; SMN2 (0.42) ALDH1A1SMN1; SMN2HIF1ARECQLCYP2C9
SCHEMBL27488524 0.79 SMN1; SMN2 (0.44) ALDH1A1SMN1; SMN2HIF1ARECQLCYP2C9
SCHEMBL12141665 0.78 ALDH1A1 (0.47) ALDH1A1SMN1; SMN2HIF1ARECQLCYP2C9
SCHEMBL28007827 0.78 TSHR (0.40) ALDH1A1SMN1; SMN2HIF1ARECQLPTPN2
SCHEMBL27953856 0.76 PPARA (0.44) ALDH1A1SMN1; SMN2HIF1ARECQLCYP3A4
SCHEMBL617935 0.76 ALDH1A1 (0.42) ALDH1A1SMN1; SMN2HIF1ACYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023098815-A1 AROMATIC COMPOUND, PHARMACEUTICAL COMPOSITION, AND APPLICATION THEREOF 上海栖臻医药科技有限公司 2023-06-08 WO disclosed