Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 7/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | ALPI | P09923 | 1/20 | 0.52 |
| ▸ | ALPG | P10696 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30474604 | 0.89 | GAA (0.65) | KDM4EHPGDGAAMEN1KMT2A | |
| SCHEMBL28568030 | 0.74 | MEN1 (0.60) | KDM4EHPGDGAAMEN1KMT2A | |
| SCHEMBL2608363 | 0.74 | MEN1 (1.00) | KDM4EHPGDGAAMEN1KMT2A | |
| SCHEMBL7716888 | 0.72 | MEN1 (0.79) | KDM4EHPGDGAAMEN1KMT2A | |
| SCHEMBL2571081 | 0.72 | MEN1 (0.79) | KDM4EHPGDGAAMEN1KMT2A | |
| SCHEMBL28268940 | 0.72 | KDM4E (0.60) | KDM4EHPGDGAAMEN1KMT2A | |
| SCHEMBL7538776 | 0.70 | MEN1 (0.74) | KDM4EHPGDGAAMEN1KMT2A | |
| SCHEMBL7538773 | 0.70 | MEN1 (0.74) | KDM4EHPGDGAAMEN1KMT2A | |
| SCHEMBL2570390 | 0.70 | MEN1 (0.74) | KDM4EHPGDGAAMEN1KMT2A | |
| SCHEMBL2570389 | 0.70 | MEN1 (0.74) | KDM4EHPGDGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110156704-B | 1,2, 4-triazole thioether derivative, crystal structure and application thereof | 湖南大学 | 2023-06-09 | — | — | CN | claimed |