SCHEMBL30475412

SCHEMBL30475412

COC(=O)c1ccc(C)c(NC(=O)N[C@@H](C)CCc2ccc(O)cc2)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LNPEP Q9UIQ6 6/20 0.57
ALDH1A1 P00352 5/20 0.53
EPHX2 P34913 1/20 0.47
ERAP2 Q6P179 2/20 0.46
SCN3A Q9NY46 1/20 0.45
TAS1R3 Q7RTX0 1/20 0.44
TAS1R1 Q7RTX1 1/20 0.44
MAPT P10636 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
TP53 P04637 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43
HPGD P15428 1/20 0.43
ALOX15 P16050 1/20 0.43
ALOX12 P18054 1/20 0.43
CYP2C19 P33261 1/20 0.43
CKS1B P61024 1/20 0.43
SKP2 Q13309 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25306345 0.89 EPHX2 (0.51) LNPEPALDH1A1EPHX2ERAP2SCN3A
SCHEMBL25306348 0.89 EPHX2 (0.51) LNPEPALDH1A1EPHX2ERAP2SCN3A
SCHEMBL25308080 0.88 EPHX2 (0.47) LNPEPALDH1A1EPHX2SCN3ATAS1R3
SCHEMBL25308361 0.88 EPHX2 (0.47) LNPEPALDH1A1EPHX2SCN3ATAS1R3
SCHEMBL25304946 0.88 EPHX2 (0.47) LNPEPALDH1A1EPHX2SCN3ATAS1R3
SCHEMBL25304719 0.87 EPHX2 (0.47) LNPEPALDH1A1EPHX2ERAP2SCN3A
SCHEMBL25304717 0.87 EPHX2 (0.47) LNPEPALDH1A1EPHX2ERAP2SCN3A
SCHEMBL25308063 0.87 EPHX2 (0.47) LNPEPALDH1A1EPHX2ERAP2SCN3A
SCHEMBL25305774 0.86 EPHX2 (0.46) LNPEPALDH1A1EPHX2SCN3ATAS1R3
SCHEMBL25305863 0.85 MEN1 (0.54) EPHX2SCN3AMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4460492-A1 COMPOUNDS CONTAINING A HYDROXYPHENYL MOIETY AND THEIR USE (INSERM) Institut National de la Santé et de la Recherche Médicale (FR) 2024-11-13 EP claimed
WO-2023131677-A1 COMPOUNDS CONTAINING A HYDROXYPHENYL MOIETY AND THEIR USE INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2023-07-13 WO claimed
EP-4460492-A1 COMPOUNDS CONTAINING A HYDROXYPHENYL MOIETY AND THEIR USE (INSERM) Institut National de la Santé et de la Recherche Médicale (FR) 2024-11-13 EP disclosed
WO-2023131677-A1 COMPOUNDS CONTAINING A HYDROXYPHENYL MOIETY AND THEIR USE INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2023-07-13 WO disclosed