SCHEMBL25306348

SCHEMBL25306348

Cc1ccc(C(=O)O)cc1NC(=O)NC(C)CCc1ccc(O)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.51
CASR P41180 1/20 0.49
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
SELL P14151 2/20 0.48
SELP P16109 2/20 0.48
MAPT P10636 1/20 0.48
SELE P16581 1/20 0.48
SCN3A Q9NY46 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.45
HTT P42858 1/20 0.45
LNPEP Q9UIQ6 2/20 0.45
ERAP2 Q6P179 1/20 0.45
ALDH1A1 P00352 2/20 0.44
KDM4E B2RXH2 1/20 0.44
POLB P06746 1/20 0.44
TAS1R3 Q7RTX0 1/20 0.43
TAS1R1 Q7RTX1 1/20 0.43
GAA P10253 1/20 0.43
MAPK1 P28482 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25306345 1.00 EPHX2 (0.51) EPHX2CASRMEN1KMT2ASELL
SCHEMBL25308080 0.90 EPHX2 (0.47) EPHX2CASRMEN1KMT2AMAPT
SCHEMBL25308361 0.90 EPHX2 (0.47) EPHX2CASRMEN1KMT2AMAPT
SCHEMBL25304946 0.90 EPHX2 (0.47) EPHX2CASRMEN1KMT2AMAPT
SCHEMBL25308063 0.89 EPHX2 (0.47) EPHX2MEN1KMT2AMAPTSCN3A
SCHEMBL30475412 0.89 LNPEP (0.57) EPHX2MEN1KMT2AMAPTSCN3A
SCHEMBL25304717 0.89 EPHX2 (0.47) EPHX2MEN1KMT2AMAPTSCN3A
SCHEMBL25304719 0.89 EPHX2 (0.47) EPHX2MEN1KMT2AMAPTSCN3A
SCHEMBL25305771 0.88 EPHX2 (0.46) EPHX2MEN1KMT2AMAPTSCN3A
SCHEMBL25305774 0.88 EPHX2 (0.46) EPHX2MEN1KMT2AMAPTSCN3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023131677-A1 COMPOUNDS CONTAINING A HYDROXYPHENYL MOIETY AND THEIR USE INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2023-07-13 WO claimed
WO-2023131677-A1 COMPOUNDS CONTAINING A HYDROXYPHENYL MOIETY AND THEIR USE INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2023-07-13 WO disclosed