Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HBB | P68871 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30493292 | 1.00 | SMN1; SMN2 (0.56) | SMN1; SMN2KDM4EGAAALDH1A1PDCD1 | |
| SCHEMBL9788869 | 0.92 | SMN1; SMN2 (0.60) | SMN1; SMN2KDM4EGAAALDH1A1PDCD1 | |
| SCHEMBL8790012 | 0.78 | CRBN (0.57) | SMN1; SMN2KDM4EPDCD1CD274CRBN | |
| SCHEMBL31334611 | 0.78 | CRBN (0.57) | SMN1; SMN2KDM4EPDCD1CD274CRBN | |
| SCHEMBL6131059 | 0.77 | SMN1; SMN2 (0.56) | SMN1; SMN2KDM4EGAAALDH1A1PDCD1 | |
| SCHEMBL31333861 | 0.77 | CRBN (0.55) | SMN1; SMN2KDM4EALDH1A1PDCD1CD274 | |
| SCHEMBL2555663 | 0.77 | CRBN (0.55) | SMN1; SMN2KDM4EALDH1A1PDCD1CD274 | |
| SCHEMBL10372621 | 0.76 | SMN1; SMN2 (0.55) | SMN1; SMN2KDM4EGAAALDH1A1PDCD1 | |
| SCHEMBL15953109 | 0.75 | KMT2A (0.41) | KDM4EALDH1A1POLBRECQLMEN1 | |
| Hydrochloric Acid SCHEMBL6633499 | 0.75 | CRBN (0.54) | SMN1; SMN2KDM4EALDH1A1PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116322700-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2023-06-23 | — | — | CN | disclosed |