SCHEMBL9788869

SCHEMBL9788869

O=C1CCC(=O)N1c1ccccn1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.60
RECQL P46063 1/20 0.52
GAA P10253 2/20 0.51
KDM4E B2RXH2 2/20 0.51
ALDH1A1 P00352 2/20 0.51
CD274 Q9NZQ7 4/20 0.50
PDCD1 Q15116 3/20 0.50
CRBN Q96SW2 1/20 0.50
POLB P06746 1/20 0.49
MAPK1 P28482 1/20 0.47
EP300 Q09472 1/20 0.47
KAT2B Q92831 1/20 0.47
ALOX5 P09917 1/20 0.46
GRIN2D O15399 1/20 0.44
GRIN3B O60391 1/20 0.44
GRIN1 Q05586 1/20 0.44
GRIN2A Q12879 1/20 0.44
GRIN2B Q13224 1/20 0.44
GRIN2C Q14957 1/20 0.44
GRIN3A Q8TCU5 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30493292 0.92 SMN1; SMN2 (0.56) SMN1; SMN2RECQLGAAKDM4EALDH1A1
SCHEMBL30475434 0.92 SMN1; SMN2 (0.56) SMN1; SMN2RECQLGAAKDM4EALDH1A1
SCHEMBL6131059 0.80 SMN1; SMN2 (0.56) SMN1; SMN2GAAKDM4EALDH1A1CD274
SCHEMBL10372621 0.79 SMN1; SMN2 (0.55) SMN1; SMN2GAAKDM4EALDH1A1CD274
SCHEMBL10772278 0.78 SMN1; SMN2 (0.50) SMN1; SMN2RECQLGAAKDM4EALDH1A1
SCHEMBL11400791 0.78 SMN1; SMN2 (0.46) SMN1; SMN2RECQLGAAKDM4EALDH1A1
SCHEMBL6131055 0.77 SMN1; SMN2 (0.53) SMN1; SMN2RECQLGAAKDM4EALDH1A1
SCHEMBL718706 0.77 SMN1; SMN2 (0.62) SMN1; SMN2GAAKDM4EALDH1A1CD274
SCHEMBL30817652 0.77 ALDH1A1 (0.73) SMN1; SMN2GAAKDM4EALDH1A1POLB
SCHEMBL7479419 0.77 ALDH1A1 (0.73) SMN1; SMN2GAAKDM4EALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107375920-A A kind of porcine reproductive and respiratory syndrome virus swine influenza virus reconstruct virosomes vaccine and its production and use 中农威特生物科技股份有限公司 2017-11-24 CN claimed
US-5000759-A Stable middle distillate fuel-oil compositions TEXACO INC. (US) 1991-03-19 US claimed
CN-113552350-A Compositions and methods for prostate cancer analysis 基因泰克公司 2021-10-26 CN disclosed
CN-108064343-B Compositions and methods for prostate cancer analysis 基因泰克公司 2021-07-09 CN disclosed
CN-107375920-A A kind of porcine reproductive and respiratory syndrome virus swine influenza virus reconstruct virosomes vaccine and its production and use 中农威特生物科技股份有限公司 2017-11-24 CN disclosed
CN-101466409-B Leptomycin derivatives SANOFI AVENTIS 2012-11-21 CN disclosed
CN-101466409-A Leptomycin derivatives SANOFI AVENTIS (FR) 2009-06-24 CN disclosed
CN-101151279-A Atazanavir conjugates and antibodies useful in immunoassay ROCHE DIAGNOSTICS OPERATIONS (CH) 2008-03-26 CN disclosed
CN-1984676-A Immunogenic peptide carrier conjugates and methods of producing same WYETH CORP (US) 2007-06-20 CN disclosed
CN-1509187-A Cytotoxic CD44 antibody immunoconjugates ���ָ��Ӣ��ķ�������Ϲ�˾ 2004-06-30 CN disclosed
US-5000759-A Stable middle distillate fuel-oil compositions TEXACO INC. (US) 1991-03-19 US disclosed