Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25822289 | 1.00 | GRM5 (0.39) | GRM5ALDH1A1SMN1; SMN2FFAR4KDM4E | |
| SCHEMBL25819188 | 0.90 | FFAR4 (0.39) | GRM5ALDH1A1SMN1; SMN2FFAR4KDM4E | |
| SCHEMBL24880555 | 0.88 | GRM5 (0.38) | GRM5ALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL30112351 | 0.88 | GRM5 (0.38) | GRM5ALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL31251917 | 0.86 | GRM5 (0.38) | GRM5ALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL30484054 | 0.85 | GRM5 (0.40) | GRM5ALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL25831440 | 0.85 | GRM5 (0.40) | GRM5ALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL29013184 | 0.85 | GRM5 (0.38) | GRM5FFAR4LMNAPDE3BPDE3A | |
| SCHEMBL25938824 | 0.84 | GRM5 (0.40) | GRM5ALDH1A1SMN1; SMN2FFAR4MAPT | |
| SCHEMBL24753633 | 0.84 | HTR1A (0.46) | FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4539849-A1 | COMPOUNDS FOR THE TARGETED DEGRADATION OF SMARCA2 | C4 Therapeutics, Inc. (US) | 2025-04-23 | — | — | EP | disclosed |
| CN-116322700-B | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2024-08-20 | — | — | CN | disclosed |
| WO-2023244764-A1 | COMPOUNDS FOR THE TARGETED DEGRADATION OF SMARCA2 | C4 THERAPEUTICS, INC. (US) | 2023-12-21 | — | — | WO | disclosed |
| CN-116322700-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2023-06-23 | — | — | CN | disclosed |