Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.55 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.51 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 3/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10561439 | 1.00 | SLC7A5 (0.55) | SLC7A5SLC1A1CTSSCTSKROCK2 | |
| SCHEMBL19664048 | 1.00 | SLC7A5 (0.55) | SLC7A5SLC1A1CTSSCTSKROCK2 | |
| SCHEMBL18788872 | 0.84 | SLC7A5 (0.56) | SLC7A5 | |
| SCHEMBL27525604 | 0.84 | SLC7A5 (0.56) | SLC7A5 | |
| SCHEMBL18481474 | 0.84 | SLC7A5 (0.56) | SLC7A5MAOB | |
| SCHEMBL3028647 | 0.84 | SLC7A5 (0.56) | SLC7A5 | |
| SCHEMBL75362 | 0.84 | SLC1A1 (0.55) | SLC7A5SLC1A1ROCK2DPP4DPP7 | |
| SCHEMBL6162540 | 0.84 | SLC1A1 (0.55) | SLC7A5SLC1A1ROCK2DPP4DPP7 | |
| SCHEMBL5739966 | 0.84 | SLC1A1 (0.55) | SLC7A5SLC1A1ROCK2DPP4DPP7 | |
| SCHEMBL10557764 | 0.84 | HTR2A (0.58) | SLC7A5DPP4DPP7DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116348109-B | Piperazine derivative, and preparation method and application thereof | 浙江海正药业股份有限公司 | 2025-01-21 | — | — | CN | disclosed |
| CN-116348109-A | Piperazine derivative, and preparation method and application thereof | 浙江海正药业股份有限公司 | 2023-06-27 | — | — | CN | disclosed |