Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 5/20 | 0.56 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3028647 | 1.00 | SLC7A5 (0.56) | SLC7A5GRIA2LTA4HTYRNOS3 | |
| SCHEMBL27525604 | 0.86 | SLC7A5 (0.56) | SLC7A5GRIA2LTA4HNOS3NOS1 | |
| SCHEMBL18481474 | 0.86 | SLC7A5 (0.56) | SLC7A5GRIA2LTA4HNOS3NOS1 | |
| SCHEMBL10561230 | 0.84 | SLC7A5 (0.55) | SLC7A5LTA4HNOS3NOS1NOS2 | |
| SCHEMBL30475895 | 0.84 | SLC7A5 (0.55) | SLC7A5 | |
| SCHEMBL17978075 | 0.84 | SLC7A5 (0.55) | SLC7A5LTA4HNOS3NOS1NOS2 | |
| SCHEMBL27350860 | 0.84 | SLC7A5 (0.55) | SLC7A5LTA4HNOS3NOS1NOS2 | |
| SCHEMBL10561439 | 0.84 | SLC7A5 (0.55) | SLC7A5 | |
| SCHEMBL19664048 | 0.84 | SLC7A5 (0.55) | SLC7A5 | |
| SCHEMBL10560530 | 0.84 | SLC7A5 (0.55) | SLC7A5LTA4HNOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10259800-B2 | Method of fluorination using iodonium ylides | THE GENERAL HOSPITAL CORPORATION (US) | 2019-04-16 | — | — | US | disclosed |
| US-10259800-B2 | Method of fluorination using iodonium ylides | THE GENERAL HOSPITAL CORPORATION (US) | 2019-04-16 | — | — | US | disclosed |
| US-20170121300-A1 | METHOD OF FLUORINATION USING IODONIUM YLIDES | THE GENERAL HOSPITAL CORPORATION | 2017-05-04 | — | — | US | disclosed |
| US-20170121300-A1 | METHOD OF FLUORINATION USING IODONIUM YLIDES | THE GENERAL HOSPITAL CORPORATION | 2017-05-04 | — | — | US | disclosed |
| US-20170121300-A1 | METHOD OF FLUORINATION USING IODONIUM YLIDES | THE GENERAL HOSPITAL CORPORATION | 2017-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170121300-A1 | METHOD OF FLUORINATION USING IODONIUM YLIDES | FLI1, ABL1, PFAS | SLC7A5 642/4885GRIA2 4312/4885LTA4H 2343/4885 |
| US-10259800-B2 | Method of fluorination using iodonium ylides | FLI1, ABL1, PFAS | SLC7A5 642/4885GRIA2 4312/4885LTA4H 2343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.